Alternative Names:

LMN; ADLD; LMN2; LMNB; Lamin B1;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:3000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Western blot analysis of Lamin B1 expression in (1) Hela cell lysate; (2) Jurkat cell lysate; (3) Mouse brain lysate; (4) Rat heart lysate with Lamin B1 Antibody.

Immunohistochemical analysis of paraffin-embedded rat liver, using Lamin B1 Antibody.

Purification:

Affinity-chromatography

Specificity:

Anti-Lamin B1 antibody detects endogenous levels of total Lamin B1

Immunogen:

A synthesized peptide derived from human Lamin B1

Description:

The nuclear lamina consists of a twoDimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.